Dermal-Soothe Anti Itch Shampoo is a remarkable breakthrough in animal care technology. Dermal-Soothe Anti-Itch Shampoo contains itch relieving Pramoxine HCl and Novasome microvesicles designed to deliver long-lasting moisture factors to the hair and epidermal layers in a great shampoo. The result is an itch relieving shampoo that leaves your pets' coat soft, supple and lustrous. Safe for use on dogs, cats and horses. Directions:Shake well. Wet coat thoroughly before applying shampoo. Work into coat until a lather is produced. Allow to stand 10-15 minutes and rinse thoroughly. As with any medicated shampoo, gloves should be worn when applying this product. Ingredients:1% Pramoxine HCl in a concentrated shampoo base with Novasome microvesicles, Colloidal Oatmeal and Skin Respiratory Factor.