A Dermasphere is a microscopic sphere made up of alternating layers (between 100 to 1000 layers). These different layers are made up of Lipophilic (oil loving) and Hydrophilic (water loving) compounds. Each Dermasphere is developed to treat specific skin conditions. The Dermasphere adheres to skin and hair to from a protective shield which continually releases medication. The main active ingredient Chitosan is derived from shells of shrimp and other crustacean shells (filter and growth enhancer). It is non-toxic, non-allergenic, non-irritating and biodegradable. Hypoallergenic Shampoo contains patented Dermaspheres specifically developed to treat dogs with sensitive skin. A gentle time released shampoo that rehydrates dry skin. It is dye, fragrance, soap-free and pH balanced.